| Astros 11 Mariners 4 - Final |
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| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | Tot |
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| Hou | 0 | 1 | 1 | 1 | 1 | 4 | 1 | 2 | 0 | 11 |
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| Sea | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 4 |
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Houston at Seattle - Wed 28-Jul-2021 |
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| Astros Pitchers | IP | BF | H | HR | K | BB | IBB | HB | ER | Win | Sav | WHIP | ERA | BABIP | FIP | kwERA |
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| Jake Odorizzi | | 5.33 | 23 | 5 | 2 | 3 | 1 | 0 | 1 | 3 | 1 | 0 | 1.125 | 5.06 | .188 | 7.97 | 4.88 |
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| Brooks Raley | | 0.67 | 4 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 3.000 | 0.00 | .000 | 9.10 | 8.40 |
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| Cristian Javier | | 0.67 | 6 | 1 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 0 | 6.000 | 13.50 | .333 | 16.60 | 11.40 |
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| Bryan Abreu | | 1.33 | 6 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1.500 | 0.00 | .400 | 1.60 | 3.40 |
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| Brandon Bielak | | 1.00 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0.000 | 0.00 | .000 | 1.10 | 1.40 |
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| Total | 9.00 | 42 | 8 | 2 | 6 | 6 | 0 | 1 | 4 | 1 | 0 | 1.556 | 4.00 | .222 | 6.99 | 5.69 |
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| Mariners Pitchers | IP | BF | H | HR | K | BB | IBB | HB | ER | Win | Sav | WHIP | ERA | BABIP | FIP | kwERA |
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| Yusei Kikuchi | | 5.00 | 25 | 7 | 1 | 7 | 2 | 0 | 0 | 3 | 0 | 0 | 1.800 | 5.40 | .400 | 4.10 | 3.00 |
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| JT Chargois | | 0.33 | 4 | 3 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 9.000 | 81.00 | .750 | 3.10 | 5.40 |
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| Anthony Misiewicz | | 0.67 | 5 | 3 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 4.500 | 13.50 | .750 | 0.10 | 3.00 |
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| Keynan Middleton | | 1.00 | 6 | 1 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 3.000 | 9.00 | .500 | 5.10 | 5.40 |
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| Ryan Weber | | 2.00 | 9 | 1 | 1 | 1 | 2 | 0 | 1 | 2 | 0 | 0 | 1.500 | 9.00 | .000 | 13.10 | 8.07 |
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| Total | 9.00 | 49 | 15 | 2 | 11 | 6 | 0 | 1 | 10 | 0 | 0 | 2.333 | 10.00 | .448 | 5.88 | 4.42 |
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