| Cardinals 8 Cubs 5 - Final |
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| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | Tot |
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| StL | 0 | 1 | 0 | 1 | 0 | 0 | 3 | 0 | 3 | 8 |
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| ChC | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 1 | 5 |
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St. Louis at Chicago - Sat 25-Sep-2021 |
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| Cardinals Pitchers | IP | BF | H | HR | K | BB | IBB | HB | ER | Win | Sav | WHIP | ERA | BABIP | FIP | kwERA |
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| Jon Lester | | 5.00 | 26 | 8 | 0 | 6 | 3 | 0 | 0 | 3 | 0 | 0 | 2.200 | 5.40 | .471 | 2.50 | 4.02 |
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| Kwang Hyun Kim | | 1.00 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1.000 | 0.00 | .333 | 3.10 | 5.40 |
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| T.J. McFarland | | 2.00 | 7 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 1.500 | 0.00 | .250 | 5.10 | 7.11 |
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| Luis García | | 1.00 | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.000 | 9.00 | .000 | 14.10 | 2.40 |
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| Total | 9.00 | 40 | 11 | 1 | 8 | 5 | 0 | 0 | 4 | 1 | 0 | 1.778 | 4.00 | .385 | 4.43 | 4.50 |
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| Cubs Pitchers | IP | BF | H | HR | K | BB | IBB | HB | ER | Win | Sav | WHIP | ERA | BABIP | FIP | kwERA |
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| Adrian Sampson | | 6.00 | 21 | 3 | 2 | 4 | 0 | 0 | 0 | 2 | 0 | 0 | 0.500 | 3.00 | .067 | 6.10 | 3.11 |
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| Codi Heuer | | 0.00 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | Inf | Inf | 1.000 | 3.10 | 5.40 |
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| Scott Effross | | 1.00 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0.000 | 0.00 | .000 | 1.10 | 1.40 |
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| Rowan Wick | | 1.00 | 3 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1.000 | 0.00 | .000 | 4.10 | 5.40 |
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| Tommy Nance | | 1.00 | 6 | 2 | 1 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 2.000 | 27.00 | .333 | 12.10 | 1.40 |
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| Total | 9.00 | 37 | 9 | 3 | 8 | 1 | 0 | 0 | 8 | 0 | 0 | 1.111 | 8.00 | .240 | 5.99 | 3.13 |
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