ST. PETERSBURG, Fla. (AP) — Michael Perez hit a go-ahead solo homer in the eighth inning and the AL East-leading Tampa Bay Rays beat the Baltimore Orioles 4-3 on Wednesday night.Perez homered to center off Mychal Givens (0-1). It was his first long ball since Aug. 10, 2018.Ryan Sherriff (1-0) worked a perfect eighth in his first big league game since May 7, 2018, due to Tommy John surgery. Diego Castillo pitched the ninth to get his first save. Ten Tampa Bay relievers have a save this season.Brandon Lowe hit his 10th homer for the Rays, who have won nine of 11. The Orioles are 8-3 on the road after losing the first two games of the series. Their only other defeat away from home came opening day at Boston.BLUE JAYS 9, RED SOX 1BUFFALO, N.Y. (AP) — Rowdy Tellez drove in four runs with two homers and a double, and Toronto beat Boston.Vladimir Guererro Jr. hit a pair of doubles, including a three-run bouncer down the left field line that keyed a four-run seventh inning for Toronto (15-14). Randal Grichuk also homered and drove in two runs.Five Toronto pitchers combined to allow three hits, struck out seven and walked three.Rookie right-hander Shun Yamaguchi (1-2) got the win in allowing one run on two hits over four innings of relief .Mitch Moreland homered for the Red Sox (10-21), who are 4-3 in their past seven since snapping a nine-game skid. Colton Brewer (0-2) got the loss in allowing four runs on five hits, including three homers, in 3 2/3 innings.PHILLIES 3, NATIONALS 2WASHINGTON (AP) — Aaron Nola threw seven strong innings, and Philadelphia took advantage of Washington's sloppy outfield defense to rally for a victory.Bryce Harper delivered the go-ahead RBI single in the seventh to help the Phillies win their third in a row. The defending World Series champion Nationals have dropped three consecutive games to drop to a season-high six games under .500.Nola (3-2) gave up two runs on five hits while striking out eight. Tommy Hunter tossed a perfect eighth, and recently acquired closer Brandon Workman escaped a two-on, one-out jam by striking out Eric Thames and Victor Robles for his second save with the Phillies and sixth overall.Rhys Hoskins had a solo homer in the third for Philadelphia.Juan Soto hit his eighth homer of the season for the Nationals. Reliever Will Harris (0-1) took the loss.Phillies manager Joe Girardi became the 65th manager in major league history to win 1,000 games, improving to 1,000-808 in 12 seasons.BRAVES 5, YANKEES 1, Game 1ATLANTA (AP) — Ian Anderson held the Yankees hitless into the sixth inning into the sixth inning and ending Gerrit Cole’s 20-game winning streak as Atlanta beat New York.Ronald Acuña Jr. returned to the lineup and led off with a 473-foot drive against Cole.Anderson (1-0) gave a depleted Atlanta rotation a huge boost. The 22-year-old right-hander didn’t allow a hit until Luke Voit connected for his team-leading 11th homer with one out in the sixth.That was the only hit Anderson allowed in six innings. He struck out six and walked two. Shane Greene worked the seventh.Dansby Swanson and Marcell Ozuna also homered off Cole (4-1), who suffered his first loss in the regular season since May 22, 2019, with Houston.WHITE SOX 10, PIRATES 3CHICAGO (AP) — José Abreu homered, Dallas Keuchel pitched six dominant innings, and surging Chicago pounded Pittsburgh as the White Sox won for the ninth time in 10 games.Abreu’s 12th home run was Chicago’s fourth of the game and broke it open. Eloy Jiménez slugged a three-run homer, Danny Mendick lined a two-run drive and Edwin Encarnacion added a solo shot for Chicago, which leads the AL with 60 home runs. Keuchel (5-2) allowed two runs on four hits and struck out seven in his third straight win. Erik González hit a solo shot off reliever Zack Burdi and Jacob Stallings drove in the Pirates’ two runs off Keuchel with a single in the sixth. Pittsburgh has lost two straight following a three-game winning streak to drop to 7-19, the worst record in the majors.Cole Tucker had two of the Pirates six hits. Trevor Williams (1-5) allowed a season-high eight runs and nine hits through six innings. ___More AP MLB: https://apnews.com/MLB and https://twitter.com/AP_Sports