ST. PETERSBURG, Fla. (AP) — Mookie Betts hit his major league-leading 16th homer, Chris Sale struck out nine in 7 2/3 innings and the Boston Red Sox beat the Tampa Bay Rays 4-2 on Tuesday night.Sale (5-1) gave up four hits and walked two. He has allowed three runs or fewer in his first 11 starts, the longest stretch by a Boston pitcher to open a season since Pedro Martinez's 12 in 2001.Joe Kelly finished the eighth, and Craig Kimbrel got into a bases-loaded jam before finishing his 14th save in 16 chances when Mallex Smith grounded into a game-ending forceout.Willy Adames made his big league debut and hit a solo home run off Sale in his second at-bat. The 22-year-old shortstop prospect went 1 for 4 with three strikeouts.Betts hit a three-run drive in the third off Jake Faria (3-3), who left two batters later because of a strained left oblique.Two hitters following Faria's departure, Wilson Ramos was taken out due to a bruised left hand after Austin Pruitt's 0-2 pitch to Xander Bogaerts bounced and struck the catcher.BRAVES 3, PHILLIES 1PHILADELPHIA (AP) — Ozzie Albies hit his 14th homer and Brandon McCarthy tossed 5 2/3 sharp innings, leading Atlanta to the victory.McCarthy (5-2) allowed one run and four hits. He is 4-0 with a 2.08 ERA against Philadelphia this season and 1-2 with a 6.60 ERA against the rest of the league.Vince Velasquez (4-5) gave up two runs — one earned — and fanned nine in 4 2/3 innings. He fell to 0-4 against the Braves.The NL East's top two teams have already met 11 times, with Atlanta winning seven games.Arodys Vizcaino finished with a perfect inning for his ninth save in 11 tries.INDIANS 10, CUBS 1CHICAGO (AP) — Jose Ramirez hit his 14th homer and the Indians routed the Cubs in their first meeting at Wrigley Field since the 2016 World Series.The AL Central leaders moved back to .500 with an easy victory against the team that beat them two years ago to end a 108-year championship drought.Ramirez got the blowout going with his three-run drive in the third. The Indians scored four times in the inning while chasing a wild Tyler Chatwood (3-4).Trevor Bauer (4-3) went six innings in his second straight scoreless start. The right-hander gave up seven hits and struck out six.Yonder Alonso had three of Cleveland's 11 hits, including a three-run double in the fifth.Chicago's Ian Happ led off the ninth with a pinch-hit homer against Josh Tomlin.NATIONALS 2, PADRES 1WASHINGTON (AP) — Bryce Harper hit his NL-leading 15th homer for Washington, and Michael Taylor's one-out double in the ninth scored the game-winning run.Juan Soto, the youngest player in the majors, reached base in all four at-bats in his second career start. The 19-year-old led off the ninth with his third walk, took second on Wilmer Difo's groundout and scored on Taylor's hit off the center-field wall against Matt Strahm (0-2).Taylor also threw out a runner at the plate for the final out in the sixth inning with the score 1-1.Sean Doolittle (2-2) struck out the side in the ninth.Franchy Cordero homered for the Padres.BLUE JAYS 5, ANGELS 3TORONTO (AP) — Kendrys Morales hit a two-run homer, J.A. Happ won his second straight start and Toronto stopped a four-game losing streak.Morales connected for his fourth homer in the Blue Jays' five-run first against Garrett Richards (4-3). Teoscar Hernandez had an RBI single.Angels outfielder Chris Young misplayed Russell Martin's first-inning line drive, allowing two runs to score and ending the longest active errorless streak in the major leagues at 236 games.Los Angeles has lost eight of 11.Happ (5-2) allowed two runs in seven innings. Tyler Clippard got three outs for his second save in three chances, finishing a four-hitter.MARLINS 5, METS 1NEW YORK (AP) — Miami's Caleb Smith pitched neatly into the seventh inning against a Mets lineup that included newcomer Jose Bautista.Derek Dietrich homered and J.T. Realmuto got three hits as the Marlins, the lowest-scoring team in the majors, ended a three-game skid. The Mets had won four in a row.Bautista signed with the Mets two days after being cut by Atlanta. He doubled and scored New York's only run on Tomas Nido's sacrifice fly.Smith (3-5) pitched with poise, giving up three hits over 6 2/3 innings.Mets right-hander Zack Wheeler struck out nine in six innings. He allowed one earned run and seven hits.___More AP baseball: https://apnews.com/tag/MLBbaseball