| Cubs | 8 | Marlins | 1 | Bot 7 |
| 18:40 | Red Sox | Brayan Bello | 2-1 3.92 | @ | Pirates | Quinn Priester | 0-0 0.00 | ||
| 18:40 | White Sox | Garrett Crochet | 1-2 3.57 | @ | Phillies | Spencer Turnbull | 1-0 1.80 | ||
| 18:40 | Angels | Tyler Anderson | 2-1 1.47 | @ | Reds | Nick Lodolo | 1-0 0.00 | ||
| 18:45 | Astros | Justin Verlander | 0-0 0.00 | @ | Nationals | MacKenzie Gore | 2-0 2.81 | ||
| 19:05 | Rays | Tyler Alexander | 1-0 6.46 | @ | Yankees | Clarke Schmidt | 1-0 3.68 | ||
| 19:10 | Athletics | Joe Boyle | 1-2 5.68 | @ | Guardians | Triston McKenzie | 1-2 6.23 | ||
| 19:20 | Rangers | Andrew Heaney | 0-2 6.75 | @ | Braves | Chris Sale | 1-1 4.58 | ||
| 19:40 | Orioles | Dean Kremer | 0-1 4.96 | @ | Royals | Alec Marsh | 2-0 4.32 | ||
| 20:10 | Tigers | Jack Flaherty | 0-1 4.91 | @ | Twins | Joe Ryan | 0-1 2.60 | ||
| 20:15 | Brewers | Freddy Peralta | 2-0 2.55 | @ | Cardinals | Kyle Gibson | 1-2 6.16 | ||
| 20:40 | Mariners | Emerson Hancock | 1-2 7.98 | @ | Rockies | Dakota Hudson | 0-3 4.15 | ||
| 21:40 | Blue Jays | Yariel RodrÃguez | 0-0 2.45 | @ | Padres | Matt Waldron | 0-1 3.14 | ||
| 22:10 | Mets | Sean Manaea | 1-1 4.30 | @ | Dodgers | Yoshinobu Yamamoto | 1-1 4.50 | ||
| 22:15 | Diamondbacks | Jordan Montgomery | 0-0 0.00 | @ | Giants | Blake Snell | 0-2 12.86 |