| Rangers | 14 | Athletics | 2 | Top 4 |
| 18:10 | Tigers | Kenta Maeda | 1-1 5.02 | @ | Guardians | Logan Allen | 3-2 5.11 | ||
| 18:40 | Blue Jays | Yariel Rodríguez | 0-1 4.11 | @ | Phillies | Cristopher Sánchez | 1-3 3.68 | ||
| 18:40 | Diamondbacks | Jordan Montgomery | 1-2 5.62 | @ | Reds | Nick Martinez | 0-2 4.78 | ||
| 18:40 | Angels | Patrick Sandoval | 1-5 5.91 | @ | Pirates | TBD | |||
| 18:45 | Orioles | Grayson Rodriguez | 4-1 3.71 | @ | Nationals | Trevor Williams | 3-0 2.27 | ||
| 18:50 | White Sox | Michael Soroka | 0-3 6.48 | @ | Rays | Zach Eflin | 1-4 4.17 | ||
| 19:05 | Astros | Justin Verlander | 1-0 2.08 | @ | Yankees | Luis Gil | 2-1 3.19 | ||
| 19:20 | Red Sox | Kutter Crawford | 2-1 1.56 | @ | Braves | Reynaldo López | 2-1 1.50 | ||
| 19:40 | Padres | Joe Musgrove | 3-3 6.37 | @ | Cubs | Shota Imanaga | 5-0 0.78 | ||
| 19:40 | Mariners | Emerson Hancock | 3-3 4.75 | @ | Twins | Bailey Ober | 3-1 4.55 | ||
| 19:40 | Brewers | Colin Rea | 3-0 2.67 | @ | Royals | Seth Lugo | 5-1 1.60 | ||
| 19:45 | Mets | José Buttó | 0-2 2.57 | @ | Cardinals | Steven Matz | 1-2 6.18 | ||
| 20:40 | Giants | Kyle Harrison | 2-1 3.79 | @ | Rockies | Dakota Hudson | 0-5 5.93 | ||
| 22:10 | Marlins | Edward Cabrera | 1-1 6.05 | @ | Dodgers | Yoshinobu Yamamoto | 3-1 2.91 |