| Date | Status | Player | Injury | Target Return? | Prognosis |
|---|
| 2017-12-20 | Day-to-Day | Zack Britton | Achilles | | The Orioles announced that Britton suffered a ruptured Achillles tendon earlier this week. There is no timetable for his return. |
| 2017-10-18 | Day-to-Day | Eduardo Rodriguez | Knee | | The Red Sox announced that Rodriguez had surgery on his right knee and is expected to return to pitching in six months. |
| 2017-10-18 | Day-to-Day | Hanley RamÃrez | Shoulder | | The Red Sox announced that Ramirez had surgery on his left shoulder and should be ready for the start of the 2018 season. |
| 2017-10-18 | Day-to-Day | Dustin Pedroia | Knee | 2018-05-16 | The Red Sox announced that Pedroia had surgery on his left knee. He's expected to miss the next 7 months or so and miss the early part of the 2018 season. |